Single Cell Manipulation Technology

The basic technology for single cell handling applied in the SICTEC project is based on inkjet-like printing of single cells confined in picoliter sized microdroplets. Prior to printing the cells are detected inside the printhead by a sensor (various sensor principles are under investigation). Based on the sensor signal the individual cells might be identified, sorted, counted etc. before they are dellivered contact free to a substrate confined in a micro droplet. This video shows some details on how the machine used for that - the single cell manipulator (SCM) - looks like and how it operates.

A typical single cell workflow

The SCM working principle (as developed during the PASCA project)